Biostatistics and Bioinformatics Shared Resource Facility
The Biostatistics and Bioinformatics Shared Resource Facility (BB SRF) is a cancer center-managed shared resource that plays a key collaborative role in providing scientific and statistical input across the entire spectrum of cancer research being performed
at the Markey Cancer Center (MCC). The mission of the BB SRF is to apply statistical principles to enhance conduct of scientific research through collaborative interactions with MCC members. To this end, our primary goal is to provide a comprehensive, centralized, and accessible biostatistics support
infrastructure staffed with high-level statistical expertise to support all phase of cancer studies: development, implementation, and post-study analyses.
The Specific Aims of the BB SRF are to:
Aim 1: Provide investigators with biostatistical expertise in study planning and design of laboratory, preclinical/animal, translational, bioinformatics, clinical and population-based studies.
Aim 2: Provide support during study conduct, including interim monitoring of studies to assess any potential adaptations in study design and/or sample size, safety/toxicity and efficacy monitoring, interim reporting for quality control and data
Aim 3: Apply state-of-the-art statistical methodologies for data analysis and interpretation of results for abstract and manuscript preparations.
Aim 4: Provide specialized expertise in data management and analysis of large and complex cancer registry and other population-based databases to facilitate utility in the conduct of research.
Aim 5: Interact with the Clinical Protocol and Data Management offices to ensure development and conduct of high-quality clinical studies.
Aim 6: Collaborate with the Cancer Research Informatics SRF in the development of database applications for accurate, timely and secure data collection and data sharing.
Aim 7: Interact with other MCC SRFs to ensure seamless provision of research support to MCC members.
Aim 8: Participate in training and teaching activities of the MCC.
Aim 9: Develop or adapt biostatistical analytical methods to better address important research questions arising from collaborations with cancer center members.
Prioritization of services
- Level 1: Collaboration with MCC members with cancer-related, peer-reviewed studies with BB SRF funding.
- Level 2: MCC investigators preparing cancer-related, peer-reviewed grant applications with proposed BB SRF funding.
- Level 3: MCC pilot/feasibility projects.
- Level 4: Data analysis, manuscript preparations of MCC investigators with BB SRF statisticians as co-authors.
- Level 5: MCC investigators developing non-peer reviewed studies (such as IITs with industry support) with request for BB SRF funding.
- Level 6: Unfunded cancer research projects that require limited statistical input.