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  • Division of Cardiovascular Medicine

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    As a cornerstone of the UK Gill Heart Institute, our mission is to improve the cardiovascular health of Kentucky and the nation by uniting excellence in patient care with ground-breaking research, outstanding education and preventive efforts. Our vision is to be among the top 10 public cardiovascular programs in the country by providing research-driven patient care and applying the latest evidence and technology.

    The division’s 30 faculty, 10 advanced-practice providers and two cardiovascular pharmacy specialists are dedicated to actively seeking treatments for heart and vascular disease. They are committed to providing the best and most appropriate care to all patients.

    Facts 

    Nearly one-third of our faculty are funded by the National Institutes of Health or private organizations such as the American Heart Association.

    Currently, four junior faculty positions are supported by career development awards.

    Adjunct member Brandon Fornwalt, MD, PhD, received a 2012 Early Independence Award from the Director of the National Institutes of Health for his pioneering work on the use of cardiac MRI in the management of congenital heart disease.

    We are home to two training grants from the National Heart Lung and Blood Institute – one for predoctoral students and one for postdoctoral fellows in cardiovascular science.

    In 2012, Alan Daugherty PhD, DSc, was appointed as Editor-in-Chief of Arteriosclerosis, Thrombosis, and Vascular Biology.

    Despite impressive progress in treating heart and vascular conditions during the past 30 years, cardiovascular disease remains the leading cause of death in Kentucky and the United States. Developing novel tools and implementing the latest medical evidence and technology are essential if we are to eliminate cardiovascular disease in the country.

    Discoveries made by our physicians and scientists have provided new diagnostic tools, therapies and better understanding of cardiovascular disease. We maintain a strong, consistent record of publications in the nation’s foremost peer-reviewed medical journals.

    We are also committed to educating physicians and scientists in training and to disseminating knowledge to local communities about advances and emerging issues in cardiovascular disease.   

    Please tour the pages of our website that describe our history, services and accomplishments.  In them, you will learn of our commitment to the highest standards of excellence in the diagnosis and treatment of cardiovascular disease and our dedication to scholarly pursuits that will improve the future of heart health in Kentucky and the nation.

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  • Research in the division spans basic science to clinical research to population studies. Investigators focused on basic science advances have laboratory space in the Saha Cardiovascular Research Center located in the Biomedical Biological Sciences Building.  Under the direction of Alan Daugherty, PhD, DSc, the Saha CVRC is home to extramurally funded programs in:  

    Atherosclerosis and aneurysm (Alan Daugherty, PhD, DSc; Dennis Bruemmer, MD, PhD; Vicky King, PhD; Hong Lu, MD, PhD; Venkat Subramanian, PhD)

    Cardiac imaging (Steve Leung, MD; Vince Sorrell, MD; Brandon Fornwalt, MD, Phd)

    Bioactive lipid mediators (Andrew Morris, PhD; Susan Smyth, MD, PhD; Ahmed Abdel-Latif, MD, MSPH)

    Platelet function and thrombosis (Zhenyu Li, MD, PhD; Susan Smyth, MD, PhD)

    Stem-cell biology (Ahmed Abdel-Latif, MD, MSPH) 

    Many of our investigators are also engaged in studies to understand the links between obesity and cardiovascular disease.  

    Research is facilitated by state-of-the-art technology for small molecule mass spectrometry (under the direction of Andrew Morris, PhD) and advance cardiovascular imaging.  Indeed, the University of Kentucky houses one of seven institutions in the country to have the state-of-the-art 7-Tesla Clinscan MRI for imaging in preclinical, animal models. Working with world leaders at the University of Virginia (Dr. Frederick Epstein’s laboratory), UK investigators have established advanced mouse cardiac MRI sequences that allow direct quantification of sub-millimeter motion from mouse hearts beating over 500 times per minute. Our Clinscan MRI has a Siemens control system identical to the MRIs used in our cardiology clinic, which facilitates direct translation of our findings in mice into a greater understanding of the human heart.

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    The division supports a clinical trial section, led by Khaled Ziada, MD, and clinical research manager Tiffany Sandlin, RN. Phase 1 - IV clinical trials are currently under way in structural heart disease, coronary artery disease, heart failure, and electrophysiology.

    Innovative catheter-based approaches to heart and vascular disease have always been a particular strength of our clinical research efforts.  We are currently the only site in Kentucky participating in the Symplicity HTN study of renal denervation for resistant hypertension. 

    Historically, we have been a top enroller in multicenter trials of novel devices for PFO closure, left atrial pressure monitoring (to treat heart failure), and ASD closure. 

    Our involvement in clinical trials makes available innovative treatments that would otherwise not exist in this region of the country. The awarding of a Clinical and Translational Science (CTSA) Program from National Institute of Health places the university in an elite group of 60 biomedical research institutions poised to tackle challenges in medicine and surgery with ground-breaking approaches. 

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  • Our physicians and staff work tirelessly to provide comprehensive and compassionate heart care to our patients, whether they need treatment for a common condition or one that requires advanced procedures and technology.

    Our inpatient services, under the direction of Charles L. Campbell, MD, are located primarily in the combined Cardiovascular and Thoracic Intensive Care Unit (CVTICU) and on the sixth floor of Pavilion H of UK Albert B. Chandler Hospital. We also provide consultative cardiology services at UK Good Samaritan Hospital.

    Many of our faculty have part-time appointments at the Lexington VA Medical Center, a fully accredited, two-division, tertiary care medical center with 199 hospital beds. David C. Booth, MD, serves as Chief of Cardiology at the Lexington VA Medical Center.

    Outpatient and outreach activities are directed by Rick McClure, MD, and have expanded across the region to seven locations and more than 16,000 visits annually.  

    Our clinical subspecialties include

    • Interventional Cardiology, led by Khaled Ziada, MD
    • Cardiovascular Imaging, led by Vincent Sorrell, MD
    • Heart Failure/Transplant/Circulatory Assistance, led by Navin Rajagopalan, MD
    • Cardiovascular Rehabilitation, led by Alison Bailey, MD
    • Pulmonary Hypertension, led by David Booth, MD
    • Structural Heart and Valve program, led by John Gurley, MD
    • Echocardiography, led by Mikel D. Smith, MD.

    The division is supported by two cardiovascular specialty-trained pharmacists – Tracy McCauley and Sara Brouse  – who actively participate in clinical, research and educational activities of the division. The division also has 10 advanced-practice providers who specialize in the management of inpatient and office practice of cardiovascular care.

  • Our Cardiovascular Diseases Fellowship program, directed by Charles Campbell, MD, and Alison Bailey, MD, offers superb clinical training in the active academic environment of UK Chandler Hospital, the affiliated Lexington VA Medical Center and UK Good Samaritan Hospital.

    Currently, we have 19 general cardiology fellows, four interventional fellows, one imaging fellow and four research fellows. The program plans to add an electrophysiology fellow in 2013.

    In addition to formal training for students, residents and fellows, we host weekly Cardiovascular Grand Rounds seminars that feature thought leaders in the field as well as lively and interactive Cardiovascular Journal Clubs.

    The excellence of our training programs has been recognized by the National Institutes of Health and other organizations such as the American Heart Association and the Society for Cardiac Angiography and Interventions.  

    Highly competitive extramural T32 support has been obtained from the National Institutes of Health for trainees in the cardiovascular area:

    The University of Kentucky Interdisciplinary Cardiovascular Training Program (Alan Daugherty, PhD, program director) supports students interested in pursuing a long-term research and teaching career in the cardiovascular sciences.

    The Research Training in Muscle Biology of Cardiopulmonary Disease Program (Michael Reid, PhD, program director) trains predoctoral and medical students for muscle research in the context of cardiopulmonary disease.

    The University of Kentucky Training Program for Clinical Scholars in Cardiovascular Science (Susan Smyth, MD, PhD, program director) is designed to prepare exceptional clinical and postdoctoral fellows to assume leadership positions directing multidisciplinary research in the field of cardiovascular medicine.

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  • Save the date

    The Division of Cardiovascular Medicine sponsors a weekly continuing education series. Seminars are held Fridays from 7:30-8:30 a.m. in room 234 of the Biological-Pharmaceutical Complex.  Please contact the host if you wish to have lunch with or meet the speaker during his or her time on campus. 


  • Save the date

    The Division of Cardiovascular Medicine sponsors a weekly continuing education series. Seminars are held Fridays from 7:30-8:30 a.m. in room 234 of the Biological-Pharmaceutical Complex.  Please contact the host if you wish to have lunch with or meet the speaker during his or her time on campus. 



Page last updated: 12/26/2013 2:03:26 PM