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Heidi L. Weiss, PhD

Cancer Center Member

Markey Research Programs:
    Drug Discovery, Delivery and Translational Therapeutics

Associate Director, Shared Resources and Director, Biostatistics Shared Resource Facility

Professor

Department of Surgery ›
College of Medicine ›

Research Focus

Design and analysis of early phase clinical trials focusing on Bayesian design and interim monitoring. Statistical analysis of transgenic, xenograft and chemically induced mouse models of cancer.

Contact Information

800 Rose Street
CC448 Roach Building
University of Kentucky
Lexington Kentucky 40536

Key Publications

  1. Massarweh S, Tham YL, Huang J, Sexton K, Weiss H, Tsimelzon A, Beyer A, Rimawi M, Cai WY, Hilsenbeck S, Fuqua S and Elledge R. A phase II neoadjuvant trial of anastrozole, fulvestrant, and gefitinib in patients with newly diagnosed estrogen receptor positive breast cancer. Breast Cancer Res Treat 129:819-27, 2011.
  2. Weiss HL, Urban DA, Grizzle WE, Cronin KA, Freedman LS, Kelloff GJ, Lieberman R. Bayesian Monitoring of a phase II chemoprevention trial in high risk cohorts for prostate cancer. Urology 57(4A):220-223, 2001.

Recent Publications

(five most recent publications via an automated list from PubMed, based on researcher’s ID and the University of Kentucky)
  1. Kenlan DE, Rychahou P, Sviripa VM, Weiss HL, Liu C, Watt DS, Evers BM.
    Fluorinated N,N'-Diarylureas As Novel Therapeutic Agents Against Cancer Stem Cells.
    Mol Cancer Ther. 2017 Mar 03.
  2. Wang Q, Zhou Y, Rychahou P, Fan TW, Lane AN, Weiss HL, Evers BM.
    Ketogenesis contributes to intestinal cell differentiation.
    Cell Death Differ. 2017 Mar;24(3):458-468.
  3. Wen YA, Xing X, Harris JW, Zaytseva YY, Mitov MI, Napier DL, Weiss HL, Mark Evers B, Gao T.
    Adipocytes activate mitochondrial fatty acid oxidation and autophagy to promote tumor growth in colon cancer.
    Cell Death Dis. 2017 Feb 02;8(2):e2593.
  4. Stewart RL, West D, Wang C, Weiss HL, Gal T, Durbin EB, O'Connor W, Chen M, O'Connor KL.
    Elevated integrin α6β4 expression is associated with venous invasion and decreased overall survival in non-small cell lung cancer.
    Hum Pathol. 2016 Aug;54:174-83.
  5. Upreti M, Jyoti A, Johnson SE, Swindell EP, Napier D, Sethi P, Chan R, Feddock JM, Weiss HL, O'Halloran TV, Evers BM.
    Radiation-enhanced therapeutic targeting of galectin-1 enriched malignant stroma in triple negative breast cancer.
    Oncotarget. 2016 Jul 05;7(27):41559-41574.